Article

Genetic and Multi-omic Risk Assessment of Alzheimer’s Disease Implicates Core Associated Biological Domains

2022-12-16

Abstract excerpt

Alzheimer’s disease (AD) is the predominant dementia globally, with heterogeneous presentation and penetrance of clinical symptoms, variable presence of mixed pathologies, potential disease subtypes, and numerous associated endophenotypes. Beyond the difficulty of designing treatments that address the core pathological characteristics of the disease, therapeutic development is challenged by the uncertainty of whic...

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Literature Corpus work: d3d75755-9aea-5220-9921-d14b136ccdda
DOI: 10.1101/2022.12.15.22283478

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