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Article

Homeostasis and immunological function of self-driven memory-phenotype CD4+ T lymphocytes.

Immunological medicine - 1 Mar 2023

Kawabe Takeshi

Abstract excerpt

CD4+ T lymphocytes play an essential role in adaptive immune responses. In pathogen infection, naïve CD4+ T cells that strongly respond to foreign antigens robustly proliferate to differentiate into effector/memory cells, contributing to elimination of the pathogen concerned. In addition to this conventional T cell activation pathway, naïve T cells can also weakly respond to self antigens in the periphery to...

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Identifiers

PMID: 36218322
DOI: 10.1080/25785826.2022.2129370

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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