Article
Memory-phenotype CD4+ T cells: a naturally arising T lymphocyte population possessing innate immune function.
International immunology - 25 Mar 2022
Kawabe Takeshi, Sher Alan
Abstract excerpt
In conventional adaptive immune responses, upon recognition of foreign antigens, naive CD4+ T lymphocytes are activated to differentiate into effector/memory cells. In addition, emerging evidence suggests that in the steady state, naive CD4+ T cells spontaneously proliferate in response to self-antigens to acquire a memory phenotype (MP) through homeostatic proliferation. This expansion is particularly profound...
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