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Article

Memory-Phenotype CD4+ T Lymphocytes: A Double-Edged Sword in Immune Responses.

The Tohoku journal of experimental medicine - 9 Apr 2026

Kawabe Takeshi

Abstract excerpt

CD4+ T lymphocytes play an essential role in adaptive immune responses and comprise naïve, effector, and memory compartments. In pathogen infection, foreign antigen (Ag)-specific naïve T lymphocytes are activated to give rise to effector and memory cells to contribute to host protection from the pathogen. In addition to the conventional activation pathway, accumulating evidence suggests that some naïve cells can...

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Identifiers

PMID: 41882837
DOI: 10.1620/tjem.2026.J040

Genes

CD4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

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