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Article

The Conventional Nature of Non-MHC-Restricted T Cells

14 Jun 2018

Abstract excerpt

The definition "unconventional T cells" identifies T lymphocytes that recognize non-peptide antigens presented by monomorphic antigen-presenting molecules. Two cell populations recognize lipid antigens and small metabolites presented by CD1 and MR1 molecules, respectively. A third cell population expressing the TCR Vγ9Vδ2 is stimulated by small phosphorylated metabolites. In the recent past, we have learnt a lot...

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PMID: 29963057
DOI: 10.3389/fimmu.2018.01365

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