Article

Native, Spatiotemporal Profiling of the Global Human Regulome

2025-06-15

Abstract excerpt

<h4>SUMMARY</h4> The regulome, comprising transcription factors, cofactors, chromatin remodelers, and other regulatory proteins, forms the core machinery by which cells interpret signals and execute gene expression programs. Despite its central role in development, disease, and drug response, the regulome remains largely uncharted at scale due to its dynamic, low-abundance, and chromatin-associated nature. Here,...

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Literature Corpus work: d66b70f6-0d54-5d9c-b9e2-6352c4426481
DOI: 10.1101/2025.06.14.659727

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