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Defining the RBPome of T helper cells to study higher order post-transcriptional gene regulation

2020-08-20

Abstract excerpt

Post-transcriptional gene regulation is complex, dynamic and ensures proper T cell function. The targeted transcripts can simultaneously respond to various factors as evident for Icos , an mRNA regulated by several RNA binding proteins (RBPs), including Roquin. However, fundamental information about the entire RBPome involved in post-transcriptional gene regulation in T cells is lacking. Here, we applied global R...

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Literature Corpus work
dad2aaad-3612-5e66-b906-1eae4b36a829
DOI
10.1101/2020.08.20.259234
Open publication

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Defining the RBPome of T helper cells to study higher order post-transcriptional gene regulationDOI 10.1101/2020.08.20.259234
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