Article

Protein composition of axonal dopamine release sites in the striatum

2022-08-31

Abstract excerpt

Mechanisms of neuromodulatory transmission in the brain remain ambiguous. Dopamine is a prototypical neuromodulator, and it was recently found that its secretion relies on active zone-like release site assemblies. Here, we use in vivo biotin-identification (iBioID) proximity proteomics in mouse striatum to isolate dopamine release site proteins enriched over the general dopamine axonal protein content. Using three...

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Literature Corpus work: d5b54061-7e81-5bd6-94b6-2d84fbdce12a
DOI: 10.1101/2022.08.31.505994

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