Article

Cortical Overgrowth in a Preclinical Forebrain Organoid Model of <i>CNTNAP2</i> -Associated Autism Spectrum Disorder

2019-08-19

Abstract excerpt

<h4>ABSTRACT</h4> Autism spectrum disorder (ASD) represents a major public health burden but translating promising treatment findings from preclinical non-human models of ASD to the clinic has remained challenging. The recent development of forebrain organoids generated from human induced pluripotent stem cells (hiPSCs) derived from subjects with brain disorders is a promising method to study human-specific neuro...

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Literature Corpus work: d54a7bc5-7ad7-55c7-adf5-e25da5cc2bce
DOI: 10.1101/739391

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