Article

Cerebral Organoids Containing an <i>AUTS2</i> Missense Variant Model Microcephaly

2022-02-24

Abstract excerpt

<h4>ABSTRACT</h4> Variants in the AUTS2 gene are associated with a broad spectrum of neurological conditions characterized by intellectual disability, microcephaly, and congenital brain malformations. Here, we use a human cerebral organoid (CO) model to investigate the pathophysiology of a heterozygous de novo missense AUTS2 variant identified in a patient with multiple neurological impairments including primary m...

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Literature Corpus work: 268d0f78-6fc0-5cfe-850b-146fdbd52fa6
DOI: 10.1101/2022.02.23.22271091

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Cerebral Organoids Containing an <i>AUTS2</i> Missense Variant Model MicrocephalyDOI 10.1101/2022.02.23.22271091Read

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