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Article

Cerebral organoids as an in vitro model to study autism spectrum disorders.

Gene therapy - 1 Sept 2023

Rabeling Alexa, Goolam Mubeen

Abstract excerpt

Autism spectrum disorders (ASDs) are a set of disorders characterised by social and communication deficits caused by numerous genetic lesions affecting brain development. Progress in ASD research has been hampered by the lack of appropriate models, as both 2D cell culture as well as animal models cannot fully recapitulate the developing human brain or the pathogenesis of ASD. Recently, cerebral organoids have...

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PMID: 35790793
DOI: 10.1038/s41434-022-00356-z

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