Roles for Synonymous Codon Usage in Protein Biogenesis.

Abstract excerpt

Owing to the degeneracy of the genetic code, a protein sequence can be encoded by many different synonymous mRNA coding sequences. Synonymous codon usage was once thought to be functionally neutral, but evidence now indicates it is shaped by evolutionary selection and affects other aspects of protein biogenesis beyond specifying the amino acid sequence of the protein. Synonymous rare codons, once thought to have...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Biological Evolution
• Share to Codon
• Share to Mutation