Article
Decoding mechanisms by which silent codon changes influence protein biogenesis and function.
The international journal of biochemistry & cell biology - 1 Jul 2015
Bali Vedrana, Bebok Zsuzsanna
Abstract excerpt
SCOPE: Synonymous codon usage has been a focus of investigation since the discovery of the genetic code and its redundancy. The occurrences of synonymous codons vary between species and within genes of the same genome, known as codon usage bias. Today, bioinformatics and experimental data allow us to compose a global view of the mechanisms by which the redundancy of the genetic code contributes to the complexity...
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