Article

Patient iPSC-derived astrocytes with high polygenic risk for schizophrenia reveals a role for mitochondrial glutamate carrier SLC25A18

2022-07-15

Abstract excerpt

<title>Abstract</title> <p>Schizophrenia is a highly heritable developmental disorder with often devastating effects on patients and their families. The causal mechanisms behind SCZ remain largely unknown, even after more than a century of research. Astrocytes are increasingly being associated with neuropsychiatric disorders including schizophrenia, yet have gained little attention in research. Therefore, in the...

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Literature Corpus work: d4ce5154-1671-592b-ac0e-deeb7e3bedec
DOI: 10.21203/rs.3.rs-1811182/v1

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