Article

An amino acid-resolution interactome for motile cilia illuminates the structure and function of ciliopathy protein complexes

2023-07-10

Abstract excerpt

Motile cilia are ancient, evolutionarily conserved organelles whose dysfunction underlies motile ciliopathies, a broad class of human diseases. Motile cilia contain myriad different proteins that assemble into an array of distinct machines, so understanding the interactions and functional hierarchies among them presents an important challenge. Here, we defined the protein interactome of motile axonemes using cross...

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Literature Corpus work: d4bf9caf-077c-58b8-98f4-d362be5a789a
DOI: 10.1101/2023.07.09.548259

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