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Ciliary protein trafficking mediated by IFT and BBSome complexes with the aid of kinesin-2 and dynein-2 motors

19 Dec 2017

Abstract excerpt

Cilia and flagella of eukaryotic cells are evolutionarily conserved organelles with a microtubule-based axoneme as a scaffold. To fulfil their functions in cellular motility, sensory reception and developmental signalling, cilia contain unique proteins, such as receptors and ion channels. The assembly and maintenance of cilia depend on protein trafficking mediated by intraflagellar transport (IFT) particles as...

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PMID: 29272450
DOI: 10.1093/jb/mvx087

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Ciliary protein trafficking mediated by IFT and BBSome complexes with the aid of kinesin-2 and dynein-2 motorsPMID 29272450Read ↗

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Unraveling the Intricate Cargo-BBSome Coupling Mechanism at the Ciliary TipSemantic proximity Read ↗

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