Article

Heterogeneity of radial spokes structural components and associated enzymes in <i>Tetrahymena</i> cilia

2023-08-12

Abstract excerpt

<h4>Summary</h4> Radial spokes, RS1-RS2-RS3, are T-shaped, multiprotein complexes that transmit regulatory signals from central apparatus to outer doublet dyneins. RSs, especially RS3, differ in morphology, protein composition, and RS base-docked IDAs. Spokes defects alter cilia beating frequency, waveform, and amplitude leading, in humans, to primary ciliary dyskinesia and infertility. In contrast to RS1 and RS2...

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Literature Corpus work: c3d0ae08-377f-5f1a-bec0-c01cbc277bb4
DOI: 10.1101/2023.08.11.551218

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