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Article

Novel transglutaminase-like peptidase and C2 domains elucidate the structure, biogenesis and evolution of the ciliary compartment.

Cell cycle (Georgetown, Tex.) - 15 Oct 2012

Zhang Dapeng, Aravind L

Abstract excerpt

In addition to their role in motility, eukaryotic cilia serve as a distinct compartment for signal transduction and regulatory sequestration of biomolecules. Recent genetic and biochemical studies have revealed an extraordinary diversity of protein complexes involved in the biogenesis of cilia during each cell cycle. Mutations in components of these complexes are at the heart of human ciliopathies such as...

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Source

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Identifiers

PMID: 22983010
DOI: 10.4161/cc.22068
PMCID: PMC3495828

Genes

NPHP1
CEP76
AHI1
NPHP4
RPGRIP1
TTL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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