Article

Intrinsic Heterogeneity of Primary Cilia Revealed Through Spatial Proteomics

2024-10-21

Abstract excerpt

<h4>Summary</h4> Primary cilia are a critical organelle found on most human cells, and their dysfunction is linked to hereditary ciliopathies with a wide phenotypic spectrum. Despite their significance, the specific roles of cilia in different cell types remain poorly understood due to limitations in analyzing ciliary protein composition. We employed antibody-based spatial proteomics to expand the Human Protein A...

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Literature Corpus work: 9a2b46d4-47e1-5e8a-96ab-0b6cb9728b80
DOI: 10.1101/2024.10.20.619273

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