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<i>Cnes2b</i> Regulates Host Resistance, Inflammatory Responses and Tissue Damage Following <i>Cryptococcus deneoformans</i> Infection

2024-09-19

Abstract excerpt

The 32.1 Mb Cnes2 chromosome 17 interval was shown to confer resistance to progressive Cryptococcus deneoformans 52D infection. To refine the location of Cnes2 host resistance genes, a subcongenic mouse strain (B6.CBA- Cnes2b ) that contains 8.7 Mb from the telomeric region of Cnes2 was created. At 28 days postinfection B6.CBA- Cnes2b mice had a lower lung fungal burden, increased lung injury, as well as mor...

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Literature Corpus work
d4656da4-b045-5fdf-8257-92f00acf68c6
DOI
10.1101/2024.09.14.613072
Open publication

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<i>Cnes2b</i> Regulates Host Resistance, Inflammatory Responses and Tissue Damage Following <i>Cryptococcus deneoformans</i> InfectionDOI 10.1101/2024.09.14.613072
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