Back to search

Article

The transcription factor Pdr802 regulates Titan cell formation, quorum sensing, and pathogenicity of <i>Cryptococcus neoformans</i>

2020-06-30

Abstract excerpt

<h4>ABSTRACT</h4> Cryptococcus neoformans is a ubiquitous, opportunistic fungal pathogen that kills almost 200,000 people worldwide each year. It is acquired when mammalian hosts inhale the infectious propagules; these are deposited in the lung and, in the context of immunocompromise, may disseminate to the brain and cause lethal meningoencephalitis. Once inside the host, C. neoformans undergoes a variety of ada...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
51a8ad12-d9a4-5c3c-bbff-b5c91e960ec6
DOI
10.1101/2020.06.29.179242
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The transcription factor Pdr802 regulates Titan cell formation, quorum sensing, and pathogenicity of <i>Cryptococcus neoformans</i>DOI 10.1101/2020.06.29.179242
The Transcription Factor Pdr802 Regulates Titan Cell Formation and Pathogenicity of Cryptococcus neoformansSemantic proximity
Titan cells formation in <i>Cryptococcus neoformans</i> is finely tuned by environmental conditions and modulated by positive and negative genetic regulatorsSemantic proximity
Coordinate genomic association of transcription factors controlled by an imported quorum sensing peptide in <i>Cryptococcus neoformans</i>Semantic proximity
A BRCT Domain-Containing Protein Induced in Early Phagocytosis Plays a Crucial Role in Mucorales PathogenesisSemantic proximity
The <i>Cryptococcus neoformans</i> Titan cell is an inducible and regulated morphotype underlying pathogenesisSemantic proximity
The enigmatic role of fungal annexins: the case of <i>Cryptococcus neoformans</i>Semantic proximity
Calcineurin contributes to RNAi-mediated transgene silencing and small interfering RNA production in the human fungal pathogen <i>Cryptococcus neoformans</i>Semantic proximity
Titan cells formation in Cryptococcus neoformans is finely tuned by environmental conditions and modulated by positive and negative genetic regulators.Semantic proximity
A trade-off between proliferation and defense in the fungal pathogen <i>Cryptococcus</i> at alkaline pH is controlled by the transcription factor GAT201Semantic proximity
<i>TUP1</i> disruption in <i>Cryptococcus neoformans</i> uncovers a peptide‐mediated density‐dependent growth phenomenon that mimics quorum sensingSemantic proximity
Phenotypic landscape of a fungal meningitis pathogen reveals its unique biologySemantic proximity
The cyclin Cln1 controls polyploid titan cell formation following a stress-induced G2 arrest in <i>Cryptococcus</i>Semantic proximity
Select a neighboring publication to make it the new centre.