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Global proteomic analysis of <i>Cryptococcus neoformans</i> clinical strains reveals significant differences between latent and lethal infection

2025-06-03

Abstract excerpt

<h4>ABSTRACT</h4> To predict the outcomes of disseminated fungal disease, a deeper understanding of host-pathogen interactions at the site of infection is needed to identify targets for clinical intervention and diagnostic development. Cryptococcus neoformans is the causative agent of cryptococcosis, the largest infectious killer of individuals living with HIV. Cryptococcal infection begins in the lungs, with lo...

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Literature Corpus work
d2eb81de-315e-5f3b-bb50-ddf23ec585d3
DOI
10.1101/2025.06.03.657666
Open publication

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