Article

Population-level variation of enhancer expression identifies novel disease mechanisms in the human brain

2021-05-14

Abstract excerpt

Identification of risk variants for neuropsychiatric diseases within enhancers underscores the importance of understanding the population-level variation of enhancers in the human brain. Besides regulating tissue- and cell-type-specific transcription of target genes, enhancers themselves can be transcribed. We expanded the catalog of known human brain transcribed enhancers by an order of magnitude by generating an...

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Literature Corpus work: d35ad3fb-85d2-5125-b103-469e309a9925
DOI: 10.1101/2021.05.14.443421

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