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Regulome-wide association study identifies enhancer properties associated with risk for schizophrenia

2021-06-15

Abstract excerpt

<h4>ABSTRACT</h4> Genetic risk for complex traits is strongly enriched in non-coding genomic regions involved in gene regulation, especially enhancers. However, we lack adequate tools to connect the characteristics of these disruptions to genetic risk. Here, we propose RWAS (Regulome Wide Association Study), a new framework to identify the characteristics of enhancers that contribute to genetic risk for disease....

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Literature Corpus work
fd3620af-66d3-5131-847e-f50441adda9f
DOI
10.1101/2021.06.14.448418
Open publication

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Regulome-wide association study identifies enhancer properties associated with risk for schizophreniaDOI 10.1101/2021.06.14.448418
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