Article

Brain transcriptional regulatory architecture and schizophrenia etiology converge between East Asian and European ancestral populations

2021-02-05

Abstract excerpt

Understanding the genetic architecture of gene expression and splicing in human brain is critical to unlocking the mechanisms of complex neuropsychiatric disorders like schizophrenia (SCZ). Large-scale brain transcriptomic studies are based primarily on populations of European (EUR) ancestry. The uniformity of mono-racial resources may limit important insights into the disease etiology. Here, we characterized brai...

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Literature Corpus work: cdf44ee5-4d15-5c79-b5c9-0075d509aa67
DOI: 10.1101/2021.02.04.922880

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