Article

Human iPSC-derived pericyte-like cells carrying the LRRK2 mutation induce a reactive phenotype and alter migration

2024-11-01

Abstract excerpt

<title>Abstract</title> <p>BACKGROUND Pericytes play a crucial role in controlling inflammation and vascular functions in the central nervous system, which are impaired in Parkinson’s disease. Still, there is a lack of studies on the impact of pericytes on neurodegenerative diseases, and their involvement in the pathology of Parkinson’s disease is unclear. Our objective was to investigate the molecular and funct...

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Literature Corpus work: d2403b6f-d704-5a8d-a570-0035fdbe4618
DOI: 10.21203/rs.3.rs-5104876/v1

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