Increased peripheral inflammation in asymptomatic leucine‐rich repeat kinase 2 mutation carriers

Abstract excerpt

BACKGROUND: We aimed to determine if peripheral or central inflammatory cytokines are altered in healthy subjects carrying a leucine-rich repeat kinase 2 (LRRK2) G2019S mutation, and thus genetically at risk of Parkinson's disease (PD). We also aimed to identify differences in inflammatory cytokines between LRRK2 G2019S-associated and idiopathic PD once the disease manifests. METHODS: Participants were...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Neurological diseases and metabolism
• Share to Parkinson's Disease Mechanisms and Treatments
• Share to Signaling Pathways in Disease