Article

LRRK2 G2019S Mutation Affects Human iPSC-Derived Endothelial Cells

2024-10-08

Abstract excerpt

The blood-brain barrier (BBB) serves as an interface between the bloodstream and central nervous system. It limits the movement of molecules and immune cells, regulates the entry of nutrients, and removes waste products from the brain. The dysfunction of the BBB has been identified in Parkinson´s disease (PD) but the role of the BBB and endothelial cells (ECs) has not been well studied. LRRK2 G2019S mutation is th...

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Literature Corpus work: c5bd4d29-5771-56f5-b2a4-b8d2f61ae7a5
DOI: 10.20944/preprints202410.0519.v1

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