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Multimodal Analysis Reveals New Genetic Effectors in Parkinson'S Disease-Related Gene LRRK2 Gly2019Ser Mutation

2021-11-29

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>Mutations in the LRRK2 gene, which encodes leucine-rich repeat kinase 2 (LRRK2), generate one of the most prevalent monogenic forms of Parkinson's disease (PD). Patients with autosomal dominant PD and apparent sporadic PD, who are clinically indistinguishable from those with idiopathic PD, are found to have LRRK2 mutations, particularly the most prevalent variant...

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Literature Corpus work
d1f6f7f6-76b5-50ba-8af4-b9c2a8b0161a
DOI
10.21203/rs.3.rs-1094033/v1
Open publication

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