Article
LRRK2 G2019S and Parkinson's disease: insight from Neuroinflammation.
Postgraduate medical journal - 21 Dec 2023
Yao Xiao-Yan, Guan Li-Na, Chen Qi, Ren Chao
Abstract excerpt
The multiple hypothesis holds that the pathogenesis of Parkinson's disease (PD) requires many factors such as heredity, environment and ageing. Mutations in Leucine-rich repeat kinase 2 (LRRK2) are recognized the risk factors of PD, and closely related to sporadic and familial PD and can regulate a variety of cellular pathways and processes. An Increasing number of studies has shown that glial...
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