Article

Computational estimates of mitral annular diameter in systole and diastole cardiac cycle reveal novel genetic determinants of valve function and disease

2020-12-04

Abstract excerpt

<h4>ABSTRACT</h4> The fibrous annulus of the mitral valve defines the functional orifice and anchors the anterior and posterior leaflets, playing an important role in normal cardiovascular physiology and valvular function. We derived automated estimates of mitral valve annular diameter in the 4-chamber view from 32,220 MRI images from the UK Biobank at ventricular systole and diastole as the basis for genome wide...

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Literature Corpus work: d1e21957-a668-5bbe-a4de-64359c38ad49
DOI: 10.1101/2020.12.02.20242206

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