Article

Genome-wide association meta-analysis supports genes involved in valve and cardiac development to associate with mitral valve prolapse

2020-07-04

Abstract excerpt

<h4>Objective</h4> Mitral valve prolapse (MVP) is a common cardiac valve disease, which affects 1 in 40 in the general population. Previous GWAS have identified six risk loci for MVP. But these loci explained only partially the genetic risk for MVP. We aim to identify additional risk loci for MVP by adding a dataset from the UK Biobank. <h4>Approaches and Results</h4> We re-analyzed 1,007/1,469 cases and 479/862 c...

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Literature Corpus work: 8f92781e-e65a-5765-812a-2f07c9f94d13
DOI: 10.1101/2020.07.02.20144774

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