Article

Genetic Architecture and Myocardial Fibrotic Remodeling in Mitral Valve Prolapse

2026-04-10

Abstract excerpt

Mitral valve prolapse (MVP) is the most common cause of primary mitral regurgitation and is associated with the development of malignant arrhythmias, often in the context of myocardial fibrosis. The genetic architecture of MVP, and whether there are genetic factors explaining why only some individuals with MVP have adverse outcomes, remains poorly understood. We performed a meta-analysis of genome-wide association...

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Literature Corpus work: 991502d7-61bb-5110-8763-25a0747c75de
DOI: 10.64898/2026.04.09.26350328

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