Article

Characterization of genomic regulation profiles in human mitral valve whole tissue to annotate genetic risk loci for mitral valve prolapse

2020-06-05

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Rationale</h4> Mitral valve prolapse (MVP) is a common valve disease that leads to mitral insufficiency, heart failure and sudden death. The identification of risk loci provided insight into its genetic architecture, although the causal variants and target genes need to be fully characterized. <h4>Objective</h4> To establish the chromatin accessibility profiles and gene regulation specific...

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Literature Corpus work: 5dfe8774-cf4f-5192-9aee-5635efe835df
DOI: 10.1101/2020.06.04.20122010

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