Article

Cardiac imaging of aortic valve area from 26,142 UK Biobank participants reveal novel genetic associations and shared genetic comorbidity with multiple disease phenotypes

2020-04-14

Abstract excerpt

<h4>ABSTRACT</h4> The aortic valve is an important determinant of cardiovascular physiology and anatomic location of common human diseases. From a sample of 26,142 European-ancestry participants, we estimated functional aortic valve area by planimetry from prospectively obtained cardiac MRI sequences of the aortic valve. A genome-wide association study of aortic valve area in these UK Biobank participants showed t...

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Literature Corpus work: 35889723-461d-5105-ac50-9a3a2ff75172
DOI: 10.1101/2020.04.09.20060012

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Cardiac imaging of aortic valve area from 26,142 UK Biobank participants reveal novel genetic associations and shared genetic comorbidity with multiple disease phenotypesDOI 10.1101/2020.04.09.20060012Read

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