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INTEGRATOR:Structural Elucidation of the INO80 Chromatin Remodeler via Experimentally Guided Molecular Simulations

2026-05-17

Abstract excerpt

The INO80 chromatin remodeling complex plays a central role in DNA repair, transcription, and replication. Yet, a comprehensive understanding of its structural organization remains incomplete due to the dynamic nature of several of its subunits and the sharing of several subunits with related remodeling complexes. Here, we report a computational model of the three-dimensional structure of the S. cerevisiae INO80...

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Literature Corpus work
d14b7b2f-ffb6-5ecb-9d53-a4096dc17c39
DOI
10.64898/2026.05.15.725493
Open publication

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