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Article

The complete structure of the human TFIIH core complex

2018-12-28

Abstract excerpt

Transcription factor IIH (TFIIH) is a heterodecameric protein complex critical for transcription initiation by RNA polymerase II and nucleotide excision DNA repair. The TFIIH core complex is sufficient for its repair functions and harbors the XPB and XPD DNA-dependent ATPase/helicase subunits, which are affected by human disease mutations. Transcription initiation additionally requires the CdK activating kinase su...

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Literature Corpus work
aa73240e-a948-5896-a339-e8e7adb2b0c8
DOI
10.1101/507723
Open publication

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