Article

PLANET-MD: Ultra-fast Proteome-scale Prediction of Allosteric Networks in Proteins

2025-06-17

Abstract excerpt

Proteins are dynamic molecules that depend on conformational flexibility to carry out functions in the cell, yet despite significant advances in the modeling of static protein structure, prediction of these dynamics remains challenging. We introduce PLANET-MD, a machine learning model that predicts dynamic protein properties from sequence or static structure with unprecedented speed and accuracy. Trained on thousa...

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Literature Corpus work: ea8c8d4e-3780-5704-8c52-50c1ed8d73ac
DOI: 10.1101/2025.06.12.659353

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