Article
The structure of nucleosome assembly protein 1.
Proceedings of the National Academy of Sciences of the United States of America - 31 Jan 2006
Park Young-Jun, Luger Karolin
Abstract excerpt
Nucleosome assembly protein 1 (NAP-1) is an integral component in the establishment, maintenance, and dynamics of eukaryotic chromatin. It shuttles histones into the nucleus, assembles nucleosomes, and promotes chromatin fluidity, thereby affecting the transcription of many genes. The 3.0 A crystal structure of yeast NAP-1 reveals a previously uncharacterized fold with implications for histone binding and...
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