Article

Direct activation of the Ras-Akt network mediates polarity and organizes protrusions in human neutrophil migration

2022-10-28

Abstract excerpt

Functions of Ras oncogenes and their downstream effectors are typically associated with cell proliferation and growth control while their role in immune cell migration has been largely unexplored. Although Ras-mediated signaling cascades have been implicated in immune response, there is no conclusive evidence to show local activation of these pathways on the plasma membrane directly regulates cell motility or pola...

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Literature Corpus work: d0f3fe5c-caa6-5cfe-b399-c291eada966c
DOI: 10.1101/2022.10.27.513966

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