Signaling dynamics distinguish high and low priority neutrophil attractant receptors

Abstract excerpt

<h4>ABSTRACT</h4> Human neutrophils respond to multiple chemical attractants to guide their migration from the vasculature to sites of infection and injury, where they clear pathogens and amplify inflammation. To properly focus their responses during this complex navigation, neutrophils distinguish between attractants to modulate their responses. They prioritize pathogen and injury derived signals over long-range...

Topics

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• Cell Adhesion Molecules Research
• Cellular transport and secretion
• Chemokine receptors and signaling
• Glycosylation and Glycoproteins Research
• Immune Response and Inflammation
• Neutrophil, Myeloperoxidase and Oxidative Mechanisms
• Receptor Mechanisms and Signaling
• T-cell and B-cell Immunology

Identifiers and source

Literature Corpus work

659bfc5c-0a22-56b5-b643-06ef2cccacd6

DOI

10.1101/2022.05.26.493652