Article

ObLiGaRe doxycycline Inducible (ODIn) Cas9 system driving pre-clinical drug discovery, from design to cancer treatment

2020-04-07

Abstract excerpt

<h4>ABSTRACT</h4> The CRISPR-Cas9 system has increased the speed and precision of genetic editing in cells and animals. However, model generation for drug development is still expensive and time-consuming, demanding more target flexibility and faster turnaround times with high reproducibility. We have generated a tightly controlled ObLiGaRe doxycycline inducible SpCas9 (ODInCas9) transgene. Targeted ObLiGaRe resu...

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Literature Corpus work: cf3f40c1-cbcc-5f87-b19c-7535ff3afcd8
DOI: 10.1101/2020.04.06.028803

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