Article

MND1 enables repair of two-ended DNA double-strand breaks

2022-08-24

Abstract excerpt

<h4>Summary</h4> Faithful and timely repair of DNA double-strand breaks (DSBs) is fundamental for the maintenance of genomic integrity. Here, we demonstrate that the meiotic recombination co-factor MND1 facilitates the repair of DSBs in somatic cells. We show that MND1 localizes to DSBs, where it stimulates DNA repair through homologous recombination (HR). Importantly, MND1 is not involved in the response to repl...

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Literature Corpus work: cf394d23-62ed-5f25-a621-f8cf42729046
DOI: 10.1101/2022.08.24.505076

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