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Article

PARP1 regulates RECQL4 recruitment for DNA double-strand break repair

2024-06-17

Abstract excerpt

<title>Abstract</title> <p>RecQ helicases, highly conserved proteins with pivotal roles in DNA replication, DNA repair, and homologous recombination, are crucial for maintaining genomic integrity. Mutations in RECQL4 have been associated with various human diseases, including Rothmund-Thomson syndrome. RECQL4 is involved in regulating major DNA repair pathways, such as homologous recombination (HR) and non-homolo...

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Literature Corpus work
1084b1c1-3530-55b3-89e2-d1cba6f9fc84
DOI
10.21203/rs.3.rs-4474234/v1
Open publication

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PARP1 regulates RECQL4 recruitment for DNA double-strand break repairDOI 10.21203/rs.3.rs-4474234/v1
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