Article

Species-specific effects of cation channel TRPM4 small-molecule inhibitors

2021-06-02

Abstract excerpt

<h4>Background</h4> The Transient Receptor Potential Melastatin member 4 ( TRPM4 ) gene encodes a calcium-activated non-selective cation channel expressed in several tissues. Mutations in TRPM4 have been reported in patients with different types of cardiac conduction defects. It is also linked to immune response and cancers, but the associated molecular mechanisms are still unclear. Thus far, 9-phenanthrol is t...

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Literature Corpus work: ce0b9d98-0678-5b6b-a93f-6ec10f88c927
DOI: 10.1101/2021.06.01.446517

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