Investigation of Novel Small Molecular TRPM4 Inhibitors in Colorectal Cancer Cells

Abstract excerpt

(1) Background: Transient receptor potential melastatin (TRPM4) ion channel aberrant expression or malfunction contributes to different types of cancer, including colorectal cancer (CRC). However, TRPM4 still needs to be validated as a potential target in anti-cancer therapy. Currently, the lack of potent and selective TRPM4 inhibitors limits further studies on TRPM4 in cancer disease models. In this study, we...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bioactive Compounds and Antitumor Agents
• Share to Ion Channels and Receptors
• Share to Phytochemicals and Antioxidant Activities