Article

Impact of APOE ε3 and ε4 genotypes on plasma proteome signatures in Alzheimer's disease

2022-04-20

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> The ε<italic>4</italic> allele of the apolipoprotein E (<italic>APOE</italic>) gene is a high-risk factor for Alzheimer's disease (AD). However, approximately 25%–40% of patients with AD do not carry the <italic>APOEe4</italic> allele, and the pathophysiological mechanisms underlying AD are less evident in these individuals. The main objective of this study was...

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Literature Corpus work: ce01430e-df33-5b8e-8d25-ef7517a8c4f7
DOI: 10.21203/rs.3.rs-1535069/v1

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