Article

AcornHRD: an HRD algorithm highly associated with anthracycline-based neoadjuvant chemotherapy in breast cancer in China

2023-12-22

Abstract excerpt

<title>Abstract</title> <p><bold>Purpose: </bold>Our study aimed to develop and validate a homologous recombination deficiency (HRD) scoring algorithm in the Chinese breast cancer population. <bold>Methods and materials</bold>: Ninety-six in-house breast cancer (BC) samples and 6 HRD-positive standard cells were analyzed by whole-genome sequencing (WGS). Besides, 122 BCs from the TCGA database were down-sampled t...

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Literature Corpus work: cdbf5756-0a09-51d4-8c7b-a03da9b6d2f2
DOI: 10.21203/rs.3.rs-3763756/v1

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