Article

Assessment of homologous recombination deficiency phenotype in breast cancers in adolescents and young adults in the clinical setting

2019-09-25

Abstract excerpt

<title>Abstract</title> <p>Background Homologous recombination deficiency (HRD), which may be associated with high efficacy of PARP inhibitor- and platinum agent-based therapies, is a prevalent phenotype of breast cancer diagnosed in adolescents and young adults (AYAs; 15–39 years old). HRD score, indicating HRD status, is not routinely assessed in the oncology clinic due to the need for genome-wide analyses. Met...

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Literature Corpus work: 1b1d78fd-8a20-5f95-a7e0-f50dce0f69f7
DOI: 10.21203/rs.2.15282/v1

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