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Article

Homologous recombination deficiency reflects the heterogeneity and monitoring treatment response for patients with breast cancer.

The journal of gene medicine - 1 Jan 2024

Long Quanyi, Wang Yunfei, Li Hongjiang

Abstract excerpt

BACKGROUND: In breast cancer (BC), homologous recombination defect (HRD) is a common carcinogenic mechanism. It is meaningful to classify BC according to HRD biomarkers and to develop a platform for identifying BC molecular features, pathological features and therapeutic responses. METHODS: In total, 109 HRD genes were collected and screened by univariate Cox regression analysis to determine the prognostic genes,...

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PMID: 37994492
DOI: 10.1002/jgm.3637

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